Background: Helicobacter pylori is a gram negative curved bacilli which is colonized in the human stomach. It causes duodental ulcer, gastritis and is associated with adenocarinoma. There might be a possible relationship between cagA, vacA and ice a genes and clinical outcomes. The aim of this study was to identify the frequency od vacA genotypes of H.pylori isolated from the upper gastrointestinal. Methods: 100 H. pylori strains were isolated from patients with different gastrointestinal disease in Azahra hospital. Vac A alleles were typed using PCR with specific primers. Finding : There were four Vac A mosaicsms, including 28 for s1a/ m1 (28%), 23 for s1b/m1 (23%), 26 for s1a/m2 (26%) and 23 for s1b/m2 (23%), s2 form was not found. Conclusion: The results showed there is no significant relationship between fifferent genotypes of vacA and the related diseases.
havaei,S A , Salehi,R , fazeli,S A , tavakoli,H and Mohajeri,P . (2015). Study of vac A genotypes of H.pylori isolated from patients with the upper gastrointestinal diseases by PCR. Navid No, 17(59), 29-35. doi: 10.22038/nnj.2015.5624
MLA
havaei,S A , , Salehi,R , , fazeli,S A , , tavakoli,H , and Mohajeri,P . "Study of vac A genotypes of H.pylori isolated from patients with the upper gastrointestinal diseases by PCR", Navid No, 17, 59, 2015, 29-35. doi: 10.22038/nnj.2015.5624
HARVARD
havaei S A, Salehi R, fazeli S A, tavakoli H, Mohajeri P. (2015). 'Study of vac A genotypes of H.pylori isolated from patients with the upper gastrointestinal diseases by PCR', Navid No, 17(59), pp. 29-35. doi: 10.22038/nnj.2015.5624
CHICAGO
S A havaei, R Salehi, S A fazeli, H tavakoli and P Mohajeri, "Study of vac A genotypes of H.pylori isolated from patients with the upper gastrointestinal diseases by PCR," Navid No, 17 59 (2015): 29-35, doi: 10.22038/nnj.2015.5624
VANCOUVER
havaei S A, Salehi R, fazeli S A, tavakoli H, Mohajeri P. Study of vac A genotypes of H.pylori isolated from patients with the upper gastrointestinal diseases by PCR. Navid No. 2015;17(59):29-35 (In Persian). doi: 10.22038/nnj.2015.5624
