Comparison of Selected Blood Characteristics in Women with Vaginal Delivery and Preterm Labor Referred to the Maternity Ward of Imam Khomeini Hospital in Dehdasht, Iran

Document Type : Original article

Authors

1 MSc in Midwifery, Kurdistan University of Medical Sciences, Kurdistan, Iran

2 Ph.D. in Biochemistry, Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran

3 Ph.D. Candidate in Medical Biotechnology, Iran University of Medical Sciences, Tehran, Iran

Abstract

Introduction: Due to the increasing number of premature births in recent years, high mortality rate of premature infants, and high risk of future disability of these children, it is necessary to obtain information on preterm labors and ways to diagnose premature neonates. This study aimed to compare the selected blood characteristics of women with term and preterm labors referring to the maternity ward of Imam Khomeini Hospital in Dehdasht, Iran.
Materials and Methods: This cross-sectional was conducted on 110 women referred to the maternity ward of Imam Khomeini Hospital in Dehdasht, Iran, during 2019. The participants were divided into two groups of the term (n=80) and preterm (n=30) labors. Simple random sampling was performed, and after obtaining the informed consent, blood iron, blood platelet, body mass index (BMI), white and red blood cell count, ferritin, and total iron-binding capacity (TIBC) were examined in this study. The data were analyzed in SPSS software through an independent t-test.
Results: The results showed that the mean blood iron, blood platelet, BMI, white blood cells, ferritin, and TIBC were higher in women with term labor, compared to those with preterm delivery (p < 0.05). Moreover, there were no significant differences between the two groups regarding the mean red blood cell count (P> 0.05).
Conclusion: Considering the necessity and importance of improving the level of healthy fertility, significance of maternal and infant health index as national health indicators, prevalence of some blood factor deficiency and its complications, and importance of normal BMI in the course of pregnancy and low-risk delivery, it is critical to pay attention to these factors to reduce preterm labors.

Keywords

References

  1. Koenig MA, Lutalo T, Zhao F, Nalugoda F, Wabwire-Mangen F, Kiwanuka N, et al. Domestic violence in rural Uganda: evidence from a community-based study. Bull World Health Organ. 2003; 81(1):53-60.
  2. Cunningham F, Leveno K, Bloom S, Spong CY, Dashe J. Williams obstetrics. 23th ed. New York: McGraw-Hill; 2010. P. 804-8.
  3. Goldenbery RL, Culhane JE, Jams JD, Romero R. Epidemiology and causes of preterm birth. Lancet. 2008; 371(9006):75-84.
  4. Layegh P, Afiat M, Farrokh D, Salehi M, Rezvani Mahmouee Z, Mardani R. Evaluation of Uterine artery indexes in Doppler sonography for predicting neonatal outcomes in preeclamptic pregnancies. Iran J Obstet Gynecol Infertil. 2016; 19(9):11-6. [in Persian]
  5. Cripe SM, O’Brien W, Gelaye B, Williams MA. Perinatal outcomes of Southeast Asians with pregnancies complicated by gestational diabetes mellitus or preeclampsia. J Immigr Minor Health. 2012; 14(5):747-53.
  6. Stamilio DM, Sehdev HM, Morgan MA, Propert K, Macones GA. Can antenatal clinical and biochemical markers predict the development of severe preeclampsia? Am J Obstet Gynecol. 2000; 182(3):589-94.
  7. Sclol TO, Hediher ML, Fiscler RL, Sheaner JW. Anemia Iron deficiency: increased risk of preterm delivery in a prospective study. Am J Clin Nutr. 1992; 55(5):785-8.
  8. Singh K, Fong YF, Arulkumaran S. Anemia in pregnancy--a cross-sectional study in Singapore. Eur J Clin Nutr. 2004; 52(1):65-70.
  9. Creasy RK, Resnik R, Lockwood CJ, Greene MF, Moore T. Maternal-fetal medicine: principles and practice. Houston, Texas: Gulf Professional Publishing; 2014. P. 1114-3.
  10.  Martel AJ. Tropical and geographical medicine. JAMA. 1991; 266(12):1704-5.
  11. Etaati Z, Jahanloo SH, Sobhani AR, Saberi P, Badrkhani SH. Lack of iron supplementation in pregnancy and its effect on maternal and fetal blood factors. Hormozgan Med J. 2003; 7(2):64-7.
  12. Bentley DP. Iron metabolism and anaemia in pregnancy. Clin Haematol. 2006; 14(3):613-28.
  13. Lo CC, Hsu JJ, Hsieh CC, Hung TH. Risk factors for spontaneous preterm delivery before 34 weeks of gestation among Taiwanese women. Taiwanese J Obstet Gynecol. 2007; 46(4):389-94.
  14. Nadafi M, Mohammad Hosseini S, Afrasiabyfar A, Momeni E, Malekzadeh GM. Association of homocysteine, vitamin and blood factors with preeclampsia in pregnant women. Armaghane Danesh. 2010; 15(2):171-80. [in Persian]
  15. Rayamajhi R, Pratap K. A comparative study between nifedipine and isoxuprine in the suppression of preterm labour. Kathmandu Univ Med J. 2003; 1(2):85-90.
  16. Bayoumeu F, Subiran-Buisset C, Baka NE, Legagneur H, Monnier-Barbarino P, Laxenaire MC. Iron therapy in iron deficiency anemia in pregnancy: intravenous route versus oral route. Eur J Obstet Gynecol Reorod Biol. 2005; 123:S15-9.
  17. Wise LA, Palmer JR, Heffner LJ, Rosenberg L. Prepregnancy body size, gestational weight gain, and risk of preterm birth in African-American women. Epidemiology. 2010; 21(2):243-52.
  18. Heaman M, Kingston D, Chalmers B, Sauve R, Lee L, Young D. Risk factors for preterm birth and small-for-gestational-age births among Canadian women. Paediatr Perinat Epidemiol. 2013; 27(1):54-61.
  19. Zangeneh M, Ebrahimi B, Veisi F, Malek Khosravi S, Rezavand N, Ghadami MR. The comparison of indices and number of platelet in normal and preeclamptic pregnant women. Iran J Obstet Gynecol Infertil. 2012; 15(25):8-13. [in Persian]
  20.  Seifi M, Farshbaf-khalili A, Aghaee H, Pourzeinali S. The relationship of iron deficiency anemia with preterm delivery in pregnant women referred to health centers of Tabriz: a case-control study. Iran J Obstet Gynecol Infertil. 2015; 18(159):8-17. [in Persian]
  21. Bondevik GT, Lie RT, Ulstein M, Kvale G. Maternal hematological status and risk of low birth weight and pretermdelivery in Nepal. Acta Obstet Gynecol Scand. 2001; 80(5):404-8.
  22. Torkestani F, Zafarghandi N, Jalali NM, Zaeri F, Emami A. Evaluation of correlation between nucleated red blood cell count in term newborns and meconium stained amniotic fluid. Daneshvar Med. 2007; 15(71):11-6. [in Persian]
  23. Hajimoradi L, Rahmani Z. The association between serum ferritin and iron parameters with preeclampsia. J Mazandaran Univ Med Sci. 2014; 24(118):81-9. [in Persian]
  24. Goldenberg RL, Culhane JF, Iams JD, Romero R. Epidemiology and causes of preterm birth. Lancet. 2008; 371(9606):75-84 .
  25. Akbarzadeh M, Zare N. Relationship between maternal hematologic concentration and BMI in primiparous women on some physiological parameters in neonates. Sci J Iran Blood Transfus Organ. 2013; 10(1):77-85.
  26. Vasheghani F, Atarod Z, Asghari F, Naghshvar F. Relationship between cervicovagind ferritin levels in 22-26 weeks of pregnant women with spontaneous preterm delivery. J Mazandaran Univ Med Sci. 2007; 17(58):65-71. [in Persian]
  27.  Haji Shafia F. The predictive value of simultaneous serum ferritin level measurement and cervicovaginal sample in 22 to 24 weeks of gestation in spontaneous preterm delivery. [Master Thesis]. Qazvin: Qazvin University of Medical Sciences; 2015. [in Persian]
Navid No
Volume 23, Issue 74
September 2020
Pages 10-18

Files

Share

How to cite

Statistics