A Survey of Knowledge regarding viral hepatitis among general population of Mashhad, Iran in 2017

Document Type : Original article

Authors

1 Blood Borne Infections Research Center, Academic Center for Education, Culture and Research (ACECR) , Razavi Khorasan Branch, Mashhad, Iran

2 Blood Borne Infections Research Center, Academic Center for Education, Culture and Research (ACECR), Razavi Khorasan Branch, Mashhad, Iran

3 Medical Students (Scientific) Association, Faculty of Medicine, Mashhad University of Medical sciences, Mashhad, Iran

4 Razavi Khorasan Province Health Center, Mashhad, Iran

Abstract

Introduction:The infections caused by hepatitis B virus (HBV) and hepatitis C virus (HCV) are the most common causes of liver injury. In this regard, this study aimed to determine the awareness of general population about these two infections in Mashhad, Iran.
Materials and Methods:In this cross-sectional study, all 15-year-individuals and older ones came to the site of the awareness campaign for viral hepatitis in the two large parks of Mashhad on July 28 in 2017 (World Hepatitis Day). The subjects were invited to complete a questionnaire with 12 multiple-choice questions about the knowledge of HBV and HCV infections. The knowledge score was calculated by giving one score to each correct answer and zero for a wrong answer or unanswered question. Data were analyzed using SPSS software (version 19).
Results:Totally, 362 individuals with a mean age of 37.6± 15.2 years answered the questions. The mean score of knowledge was 48.38±20.18. The highest percentage of the correct answers was related to the meaning of the word “hepatitis” (76.8%), and the lowest rate was related to the necessity of HBV vaccination for all the community (21.5%). Furthermore, in this study, 68% of the people stated that HBV carriers could get married; however, 41.7% believed that mothers with HBV infection should avoid breastfeeding. There was no significant relationship between the knowledge of hepatitis with age (P=0.07), gender (P=0.92), marital status (P=0.14), and educational level (P=0.08).
Conclusion:Our findings revealed a low level of public awareness about the transmission and prevention routes of HBV and HCV infections in Mashhad, Iran.

Keywords


1.     Trépo C, Chan HL, Lok A. Hepatitis B virus infection. Lancet. 2014; 384(9959):2053-63.
2.     Messina JP, Humphreys I, Flaxman A, Brown A, Cooke GS, Pybus OG, et al. Global distribution and prevalence of hepatitis C virus genotypes. Hepatology. 2015; 61(1):77-87.
3.     Chang ML, Liaw YF. Hepatitis B flares in chronic hepatitis B: pathogenesis, natural course, and management. J Hepatol. 2014; 61(6):1407-17.
4.     Gane E, Kershenobich D, Seguin‐Devaux C, Kristian P, Aho I, Dalgard O, et al. Strategies to manage hepatitis C virus (HCV) infection disease burden–volume 2. J Viral Hepat. 2015; 22(Suppl 1):46-73.
5.     Polaris Observatory HCV Collaborators. Global prevalence and genotype distribution of hepatitis C virus infection in 2015: a modelling study. Lancet Gastroenterol Hepatol. 2017; 2(3):161-76.
6.     Kabir A, Tabatabaei SV, Khaleghi S, Agah S, Faghihi Kashani AH, Moghimi M, et al. Knowledge, attitudes and practice of Iranian medical specialists regarding hepatitis B and C. Hepat Mon. 2010; 10(3):176-82.
7.     Ott JJ, Stevens GA, Groeger J, Wiersma ST. Global epidemiology of hepatitis B virus infection: new estimates of age-specific HBsAg seroprevalence and endemicity. Vaccine. 2012; 30(12):2212-9.
8.     Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012; 380(9859):2095-128.
9.     Salehi-Vaziri M, Sadeghi F, Almasi Hashiani A, Gholami Fesharaki M, Alavian SM. Hepatitis B virus infection in the general population of Iran: an updated systematic review and meta-analysis. Hepat Mon. 2016; 16(4):e35577.
10.  Alavian SM. Hepatitis B virus infection in Iran; Changing the epidemiology. Arch Clin Infect Dis. 2010; 5(1):51-61.
11.  Adibi P, Ghassemian R, Alavian SM, Ranjbar M, Mohammadalizadeh AH, Nematizadeh F, et al. Effectiveness of hepatitis B vaccination in children of chronic hepatitis B mothers. Saudi Med J. 2004; 25(10):1414-8.
12.  Wen Y, Zheng YX, Tan DM. A comprehensive long-term prognosis of chronic hepatitis C patients with antiviral therapy: a meta-analysis of studies from 2008 to 2014. Hepat Mon. 2015; 15(5):e27181.
13.  Razavi H, Waked I, Sarrazin C, Myers R, Idilman R, Calinas F, et al. The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm. J Viral Hepat. 2014; 21(Suppl 1):34-59.
14.  Hatzakis A, Chulanov V, Gadano AC, Bergin C, Ben‐Ari Z, Mossong J, et al. The present and future disease burden of hepatitis C virus (HCV) infections with today's treatment paradigm–volume 2. J Viral Hepat. 2015; 22(Suppl 1):26-45.
15.  Sibley A, Han K, Abourached A, Lesmana L, Makara M, Jafri W, et al. The present and future disease burden of hepatitis C virus infections with today's treatment paradigm–volume 3. J Viral Hepat. 2015; 22(Suppl 4):21-41.
16.  Gower E, Estes C, Blach S, Razavi-Shearer K, Razavi H. Global epidemiology and genotype distribution of the hepatitis C virus infection. J Hepatol. 2014; 61(1 Suppl):S45-57.
17.  Sievert W, Altraif I, Razavi HA, Abdo A, Ahmed EA, Alomair A, et al. A systematic review of hepatitis C virus epidemiology in Asia, Australia and Egypt. Liver Int. 2011; 31(Suppl 2):61-80.
18.  Pourhoseingholi MA, Ashtari S, Alavian SM. Sofosbuvir vs. combination of pegylated interferon and ribavirin; how much shall pay for Iranian patients? Hepat Mon. 2014; 14(11):e25540.
19.  Hesamizadeh K, Sharafi H, Rezaee-Zavareh MS, Behnava B, Alavian SM. Next steps toward eradication of hepatitis C in the era of direct acting antivirals. Hepat Mon. 2016; 16(4):e37089.
20.  Al-Jabri AA, Al-Adawi S, Al-Abri JH, Al-Dhahry SH. Awareness of hepatitis B virus among undergraduate medical and non-medical students. Saudi Med J. 2004; 25(4):484-7.
21.  Mahdavi A, Dadkhah B, Mohammadi MA, Mozaffari N. Survey on knowledge and attitude of above 15 years old persons about hepatitis B in Ardebil city 2002. J Nasibeh Facul Nurs Midwifery. 2002; 4(5):5-10.
22.  Crutzen R, Göritz AS. Public awareness and practical knowledge regarding Hepatitis A, B, and C: a two-country survey. J Infect Public Health. 2012; 5(2):
195-8.
23.  Chrusch C, Minuk G. Public knowledge about hepatitis B-related issues in Korea. Can J Infect Dis Med Microbiol. 1996; 7(1):53-5.
24.  Delfan AA, Mosavi MN, Ghasemzadeh F, Yaganeh MA, Ikani AH. A study of the degree of women hairdressers in Nowshahr and Chaloos about the diseases of AIDS and hepatitis. Quart J Woman Hyg. 2010; 1(1):115-26. [in Persian] 
25.  Wiecha JM. Differences in knowledge of hepatitis B among Vietnamese, African-American, Hispanic, and white adolescents in Worcester, Massachusetts. Pediatrics. 1999; 104(5 Pt 2):1212-6.
26.  Zabihi A, Hajian K. Assessment of the effect of education program on knowledge, attitude and. Hormozgan Med J. 2004; 8(3):133-8.
27.  Karimi-Sari H, Tajik M, Bayatpoor ME, Sharafi H, Alavian SM. Public awareness campaign and knowledge of Iranian (Bio) medical students regarding hepatitis B and C infections. Hepat Mon. 2017; 17(5):e45929.
28.  Fariba G, Abolfazl M, Narges M. A survey of the students' knowledge about hepatitis in Shiraz University of Medical Sciences. Hepat Mon. 2006; 2:59-62.
29.  Joukar F, Mansour-Ghanaei F, Naghipour MR, Hasandokht T. Nurses’ knowledge toward hepatitis B and hepatitis C in Guilan, Iran. Open Nurs J. 2017; 11:34-42.
30.  Rabiee M, Kazennezhad E. Knowledge and attitude of general dentists regarding HIV and hepatitis infections in Rasht. Res Med Educ. 2012; 4(1):58-67. [in Persian]
31.  Karimiankakolaki Z, Baghianimoghadam MH, Gerayllo S, Samani NS, Hadipour H. A survey of knowledge, individual perceived risk, general perceived risk, and behavioral intentions regarding hepatitis B among students in the faculty of nursing, midwifery and health at Shahrekord Islamic Azad University in 2014. Hepat Mon. 2016; 16(7):e35058.
32.  Ahmadi Z, Hosseni MS, Yaghmaei F, Anisian A. Knowledge, attitudes and practices of cleaning staff regarding hepatitis B virus. Facul Nurs Midwifery Quart. 2007; 16(57):43-9. [in Persian]
33.  Memar N. Knowledge of people over 15 years old about prophylaxis and transferring of AIDS and hepatitis B in Sanandaj. J Guilan Univ Med Sci. 2001; 10(37-38):13-8. [in Persian]