Evaluate the sero-epidemiology of Toxoplasma gondii in patients referred to Ghaem hospital, Mashhad, Iran

Document Type : Original article

Authors

1 Departments of Mycology and Parasitology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

2 Departments of Mycology and Parasitology, School of Medicine, Tehran University of Medical Sciences, Tehran , Iran

3 Infectious Diseases Research Center, Kashan University of Medical Sciences, Kashan, IR Iran. Department of Microbiology and Immunology, School of Medicine, Kashan University of Medical Sciences, Kashan, Iran

Abstract

Abstract
Introduction: Toxoplasma gondii is an obligate intracellular protozoan with a global prevalence, which infects a wide range of hosts such as humans, domestic mammals, and birds. Humans and other vertebrates are indirectly infected with the parasite through ingesting oocytes. We aimed to evaluate the sero-epidemiology of Toxoplasma gondii in patients visiting Ghaem Hospital, Mashhad, Iran, in 2015.
Materials and Methods: We performed a descriptive cross-sectional study of 306 patients visiting Ghaem Hospital, Mashhad, Iran, in 2015. In case of the patients’ consent, a demographics form was completed by a trained individual, and 5 cc of blood was simultaneously drawn for the detection of toxoplasmosis. The blood samples were centrifuged at 2000 rpm for 10 min. Then, ELISA was carried out for measuring the anti-Toxoplasma gondii immunoglobulin G (IgG) and immunoglobulin M (IgM). Finally, to analyze the data, t-test and Fisher’s exact test were run in SPSS, version 22.
Results: The mean age of the patients was 25.56±5.8 years. Of the 306 patients, 270 (88.2%) were female and 36 (11.8%) were male. We found a significant relationship between age and the prevalence of Toxoplasma gondii (P<0.05). However, there was no significant association between gender and the prevalence of this parasite (P˃0.05). The overall prevalence of IgG specific for T. gondii was 34%, this rate among women and men was 34.4% and 33.6%, respectively. In total, the prevalence of IgM for T. gondii was 6.6%.
Conclusion: Our study showed that the seroprevalence of toxoplasmosis in Mashhad, like other regions of Iran, is high. Thus, preventive measures should be adopted

Keywords

References

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Navid No
Volume 21, Issue 65
May 2018
Pages 42-48

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